Preoperative coagulopathy and blood transfusion requirements in children with intraventricular lesions…

Cohort studyChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery· Dec 2024

Preoperative coagulopathy and blood transfusion requirements in children with intraventricular lesions undergoing neurosurgery: a retrospective cohort study.

Mathangi Krishnakumar, Shweta Naik, Amit Goyal … Pallavi Pandey

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Transfusion MedicineCohort studyQ3IF 1.3

Preoperative coagulopathy found in nearly a third of children before intraventricular neurosurgery

Preoperative coagulopathy and blood transfusion requirements in children with intraventricular lesions undergoing neurosurgery: a retrospective cohort study.

Mathangi Krishnakumar … Pallavi Pandey

Child's nervous system · Dec 2024 · Q3 in General Medicine

Background

Pediatric patients undergoing neurosurgery pose risk of perioperative hemorrhage and clotting dysfunction which is increased in tumors with high vascularity, endothelial exposure, and necrosis.

Purpose

The present study aimed to study the preoperative coagulation and transfusion profile of pediatric patients undergoing neurosurgery for intraventricular lesions.

Methods

A retrospective study of all paediatric patients who underwent surgery for intraventricular lesion was included from June 2014 to June 2022.

n = 98 patients

30.7%

Results

30.7%

nearly a third of children had abnormal clotting before surgery

n = 98 patients

More results

A total of 98 patients underwent surgery, the median age was 11.1 years (1.0 to 17.0), with a male predominance (50.9%).

The median blood loss during surgery was 500 mL (300-812.5).

The median ICU stay and hospital stay was 6 days (3-10) and 14 days (4-77), respectively.

More results

The mortality rate in the study population was 7.7%.

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Conclusion · 1 of 2

This study highlights the multifactorial nature of perioperative blood loss and transfusion requirements in pediatric patients undergoing surgery for intraventricular lesions.

Conclusion · 2 of 2

Factors such as tumor histopathology, preoperative hemoglobin levels, and surgical duration play a crucial role in determining transfusion needs.