A multimodal approach to early detection of anthracycline-induced cardiotoxicity: complementary roles of left ventricular global longitudinal strain, left atrial reservoir strain, and high-sensitivity troponin I.

Anthracycline-based chemotherapy is highly effective in breast cancer treatment but is limited by dose-dependent cardiotoxicity.

To evaluate whether a multimodal surveillance strategy integrating left ventricular global longitudinal strain (left ventricular global longitudinal strain), left atrial reservoir strain (LASr), and high-sensitivity troponin I (hs-TnI) can predict early anthracycline-induced cardiotoxicity.