A 1-Hour Resuscitation Bundle for Prehospital Management of Septic Shock.

The primary outcome was 28-day all-cause mortality.

Secondary outcomes included mortality rates in the ICU, at hospital discharge, and at 90 days, time alive free of vasopressor drugs, invasive mechanical ventilation, renal replacement therapy, and ICU and hospital lengths of stay.

Of 398 participants, 17 did not consent; therefore, 381 participants (96%; mean age, 67 ± 15 yr) were analyzed.

The intracluster correlation coefficient was estimated at 0.005 ± 0.002.