Allergic Contact Dermatitis to Pure Henna: A Systematic Review.

ReviewContact dermatitis· Jul 2026

Allergic Contact Dermatitis to Pure Henna: A Systematic Review.

Mounira Ben Yahia, Mouna Korbi, Hichem Belhadjali … Jameleddine Zili

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Allergy & ImmunologyReviewClinical practiceQ3IF 1.9

Systematic review found only 13 confirmed cases of pure henna allergic contact dermatitis.

Allergic Contact Dermatitis to Pure Henna: A Systematic Review.

Mounira Ben Yahia … Jameleddine Zili

Contact dermatitis · Jul 2026 · Q3 in Immunology & Allergy

Background

Henna has traditionally been considered safe as a natural dye for hair, skin and nails.

Purpose

This review aims to provide a focused clinical overview of allergic contact dermatitis (allergic contact dermatitis) caused specifically by pure henna.

Methods

We performed a systematic review of studies reporting on cases of allergic contact dermatitis to pure henna.

n = 731 records

13

Results

13

just 13 verified cases worldwide, true henna allergy is rare

n = 731 records

More results

However, recent reports of dermatitis are increasing.

While often linked to para-phenyldiamine (para-phenyldiamine) additives, allergic reactions to pure henna are also emerging.

Eligible studies required patch test-confirmed allergic contact dermatitis to pure henna, excluding black henna, additives and reviews.

More results

Two reviewers independently screened titles, abstracts and full texts.

“

Conclusion

Clinicians should remain aware of this uncommon but possible allergy.

Allergic Contact Dermatitis to Pure Henna: A Systematic Review.

Allergic Contact Dermatitis to Pure Henna: A Systematic Review.

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