Thirty-Year Trends (1991-2020) in Head and Neck Cancer Incidence Rates: Hanoi Cancer Registry, Vietnam.
Head and neck cancer incidence rose, then declined after peaking in 2006-2010.
Thirty-Year Trends (1991-2020) in Head and Neck Cancer Incidence Rates: Hanoi Cancer Registry, Vietnam.
Head and neck cancers (head and neck cancers) remain a major contemporary public health challenge, yet few population-based studies have examined the long-term incidence trends of head and neck cancers in low- and middle-income countries.
Using International Classification of Diseases, 10th Revision code data from the Hanoi Cancer Registry (1991-2020), we examined 30-year trends in head and neck cancers incidence rates using age-standardized incidence rates (age-standardized incidence rates).
cancer rates climbed for years, then began falling after this peak
A total of 19,589 head and neck cancers cases were identified (74% men).
The proportion of male cases of head and neck cancers increased from 62.2% in 1991-1995 to 79% in 2016-2020.
Nasopharyngeal and sinonasal cancers decreased from 68% to 21% of male cases and from 59% to 36% of female cases.
Joinpoint and age-period-cohort analyses indicated a strong period effect peaking in 2006-2010 and declining risk among post-1950 birth cohorts.
Over the 30-year study period, we observed a growing male predominance of head and neck cancers, a shift in burden toward oral cavity tumors over time, and a widening male-to-female disparity in several head and neck cancers primary site cancers.
Our findings highlight an evolving epidemiologic transition in Northern Vietnam, underscoring the need for strengthened surveillance, screening, and targeted prevention and control strategies.