Pathogens in the Nasopharynx Before and After Antibiotic Treatment for Acute Otitis Media. | ScholarDeck

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Pathogens in the Nasopharynx Before and After Antibiotic Treatment for Acute Otitis Media.

New research · Otolaryngology (ENT)

The Pediatric infectious disease journal · 2mo

Randomized trialThe Pediatric infectious disease journal· Aug 2026

Pathogens in the Nasopharynx Before and After Antibiotic Treatment for Acute Otitis Media.

Hanna Björn, Nader Shaikh, Miia K Laine … Paula A Tähtinen

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Otology & HearingRandomized trialTreatmentQ1IF 1.7

Haemophilus influenzae persists in the nasopharynx despite antibiotics for acute otitis media

Pathogens in the Nasopharynx Before and After Antibiotic Treatment for Acute Otitis Media.

Hanna Björn … Paula A Tähtinen

The Pediatric infectious disease journal · Aug 2026

Background

Limited data exist on whether the timing or duration of treatment for acute otitis media (acute otitis media) affects nasopharyngeal carriage.

Methods

We included children aged 6-35 months with acute otitis media who had nasopharyngeal samples collected both before and after treatment.

Results

antibiotics failed to clear H influenzae in most children

S. pneumoniae

78%

M. catarrhalis

85%

H. influenzae

20%

More results

The timing of treatment did not affect the eradication rates of nasopharyngeal pathogens.

“

Conclusion

In most cases, H. influenzae carriage in the nasopharynx persisted despite antibiotic treatment with amoxicillin-clavulanate. This should be considered when choosing antibiotic treatment for children with a relapse of acute otitis media.

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