Cytotoxic Lesions of the Corpus Callosum after Aneurysmal Subarachnoid Hemorrhage and Risk of Shunt-Dependent Chronic Hydrocephalus.

The primary outcome was shunt-dependent chronic hydrocephalus, and the secondary outcome was unfavorable functional outcome (modified Rankin Scale score 3-6 at discharge or at approximately day 60).

Among 230 patients, 68 (29.6%) had cytotoxic lesions of the corpus callosum (small-type, 44 [19.1%]; large-type, 24 [10.4%]), and 62 (27.0%) developed shunt-dependent chronic hydrocephalus.

For large-type cytotoxic lesions of the corpus callosum, point estimates for both outcomes were elevated, but the 95% confidence interval included 1.0.