Collateral status and outcomes in ICAS-LVO: insights from the RESCUE-ICAS registry.
Stenting associated with higher odds of 90-day functional independence in intracranial atherosclerosis-related large-vessel occlusion stroke.
Collateral status and outcomes in ICAS-LVO: insights from the RESCUE-ICAS registry.
Collateral circulation influences outcomes in large-vessel occlusion (large-vessel occlusion) stroke, yet its modifying effect on endovascular therapy for intracranial atherosclerosis-related large-vessel occlusion (ICAS-large-vessel occlusion) remains uncertain.
This study evaluated whether collateral status alters the association between stent-assisted thrombectomy and outcomes in anterior-circulation ICAS-LVO.
Were treated with mechanical thrombectomy (mechanical thrombectomy) alone or mechanical thrombectomy with adjunctive stenting.
stenting more than triples the odds of 90-day functional independence
Among 271 patients, 172 (63.5% ) had good, and 99 (36.5%) had poor collaterals.
No significant interactions were observed for mortality (p = 0.847) or sICH (p = 0.909).
A significant adjusted interaction was present for final recanalization (interaction OR 8.35, p = 0.044).
In anterior-circulation ICAS-LVO, adjunctive stenting was associated with improved functional outcomes across collateral strata, with collateral status showing some modification of the stent effect on angiographic success.