First multicenter experience with the SOFIA 88 super-large-bore aspiration catheter in mechanical…

Cohort studyJournal of neurointerventional surgery· Jul 2026

First multicenter experience with the SOFIA 88 super-large-bore aspiration catheter in mechanical thrombectomy.

Sophia Hohenstatt, Răzvan Alexandru Radu, Anca Negrila … Markus A Möhlenbruch

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NeuroendovascularCohort studyClinical practiceQ1IF 4.6

SOFIA 88 achieved final successful reperfusion in most large vessel occlusion thrombectomies.

First multicenter experience with the SOFIA 88 super-large-bore aspiration catheter in mechanical thrombectomy.

Sophia Hohenstatt … Markus A Möhlenbruch

Journal of neurointerventional surgery · Jul 2026 · Q1 in Surgery

Background

Super-large-bore aspiration catheters are designed to improve clot engagement and aspiration efficiency during mechanical thrombectomy.

Methods

This retrospective multicenter European registry included consecutive patients treated with SOFIA 88 for anterior circulation large vessel occlusion involving the internal carotid artery or M1.

n = 81 cases

97.5%

Results

97.5%

reperfusion succeeded in nearly all thrombectomies

n = 81 cases

More results

SOFIA 88 reached the thrombus-vessel interface in 67/81 cases (82.7%), most often using smaller-catheter support (57/81, 70.4%).

SOFIA 88 standalone first-pass effect occurred in 32/81 patients (39.5%) using the full real-world cohort denominator and in 32/67 patients (47.8%) among cases with successful SOFIA 88 target access.

More results

Procedural adverse events occurred in 3/81 (3.7%), embolization to new territory in 1/81 (1.2%), and symptomatic intracranial hemorrhage in 5/81 (6.2%).

No device-related adverse events occurred.

“

Conclusion · 1 of 2

SOFIA 88 showed feasible target access, high final reperfusion, favorable standalone first-pass performance after successful target access, and acceptable early safety.

Conclusion · 2 of 2

Further prospective studies are warranted to define optimal patient selection, delivery strategies, and the role of SOFIA 88 in contemporary thrombectomy practice.

First multicenter experience with the SOFIA 88 super-large-bore aspiration catheter in mechanical thrombectomy.

First multicenter experience with the SOFIA 88 super-large-bore aspiration catheter in mechanical thrombectomy.

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