Contemporary Trends in the Surgical and Systemic Management of Muscle-Invasive Bladder Cancer: Insights From a Nationwide Multicenter Cohort in Turkey Over 2 Decades.

Urothelial carcinoma was the predominant histology, with variant histology observed in 5.2% of cases.

Orthotopic neobladder use decreased significantly (p<0.001), remaining below 15% overall despite a transient increase between 2008 and 2010.

Surgical approaches changed significantly over time (p<0.001), with increasing adoption of minimally invasive techniques, although open radical cystectomy remained predominant (83.0%).

Pathologically, 46.3% had ≥pT3 disease and 24.8% had lymph node metastasis.