Integrating contrast-enhanced ultrasound to optimize margin delineation in Mohs micrographic surgery for primary dermatofibrosarcoma protuberans: a retrospective cohort study.

Peripheral margin positivity was reduced from 17.4% to 5.1% (P = 0.020).

These findings were consistent across sensitivity analyses and in the propensity score-matched cohort (aIRR, 0.309; P = 0.033).

The relative effect was most pronounced in the high-risk stratum (IRR, 0.124; P = 0.041), although interaction testing was not statistically significant (P = 0.077).

No significant differences were observed in deep or total stages, likely due to ultrasound depth limitations.