Real-world use of intravenous ferric derisomaltose in Brazilian patients with iron deficiency anemia.

StudyHematology, transfusion and cell therapy· Jul 2026

Real-world use of intravenous ferric derisomaltose in Brazilian patients with iron deficiency anemia.

Lauro Augusto Caetano Leite, Gisele Dos Santos Barros, Thomas Azevedo do Carmo, Rodolfo Delfini Cançado

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Hemoglobin rose ≥2 g/dL by week 8 in 81% of patients on ferric derisomaltose.

Real-world use of intravenous ferric derisomaltose in Brazilian patients with iron deficiency anemia.

Lauro Augusto Caetano Leite … Rodolfo Delfini Cançado

Hematology, transfusion and cell therapy · Jul 2026

Background

Iron deficiency anemia remains a major global health concern, especially among women, children, and people with chronic illnesses.

Purpose

This study aimed to assess the effectiveness and safety of intravenous ferric derisomaltose in patients with iron deficiency anemia who could not tolerate or did not respond to oral iron.

Methods

This was a prospective, open-label, single-center trial conducted in São Paulo, Brazil.

Results

iron therapy raised hemoglobin substantially in most patients by week 8

Hb increase ≥2 g/dL

81%

Hb increase ≥3 g/dL

54%

More results

Thirty patients were treated with 25 requiring a second infusion.

Significant increases in hemoglobin, serum ferritin, transferrin saturation, and reticulocyte hemoglobin content were seen at both time points.

More results

Four (8%) mild adverse events occurred and three patients (10%) experienced transient, asymptomatic hypophosphatemia, which resolved without intervention.

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Conclusion · 1 of 2

This study contributes to the growing evidence supporting the use of intravenous ferric derisomaltose as a safe and effective alternative for distinct populations with iron deficiency anemia.

Conclusion · 2 of 2

In this real-world clinical setting, the treatment is effective for treating patients with iron deficiency, providing rapid hematologic recovery with a favorable safety profile.

Real-world use of intravenous ferric derisomaltose in Brazilian patients with iron deficiency anemia.

Real-world use of intravenous ferric derisomaltose in Brazilian patients with iron deficiency anemia.

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