Analysis of Clinical Characteristics and Risk Factors of Pediatric Macrolide-Resistant Mycoplasma pneumoniae Pneumonia from 2023 to 2025: A Single-Center Retrospective Study.

Compared with macrolide-susceptible MP pneumonia (macrolide-susceptible MPP) patients, those with macrolide-resistant MP pneumonia (macrolide-resistant MPP) had significantly shorter fever duration (median 5 vs 7 days) and hospital stay (median 9 vs 11 days), but more frequently received alternative antibiotics and glucocorticoids.

Macrolide-resistant MPP patients showed elevated white blood cell counts, more pulmonary consolidation, and higher rates of tracheal occlusion.

However, resistance genes were not significantly linked to severe MP pneumonia.