Persistent CD4 + lymphopenia is associated with recurrent Nocardia farcinica infection and acquired resistance in an AIDS patient: a case report with immunological warning.

On current admission (day 1), he was readmitted with high fever and sepsis.

Blood cultures flagged positive at 25 hours and were identified as Nocardia farcinica .

He received intravenous imipenem plus amikacin for 14 days, followed by oral linezolid for 6 weeks.

At the last follow-up (approximately one year after discharge), his CD4 + had risen to only 11 cells/μL, and he had no further nocardial infection.