Association of systemic lupus erythematosus with 90-day readmission following heart failure hospitalization: A national readmission database (NRD) analysis, 2016-2017.
Systemic lupus erythematosus linked to higher 90-day readmission after heart failure hospitalization.
Association of systemic lupus erythematosus with 90-day readmission following heart failure hospitalization: A national readmission database (NRD) analysis, 2016-2017.
Systemic lupus erythematosus is a chronic autoimmune disease associated with heightened cardiovascular risk.
This study aimed to evaluate whether systemic lupus erythematosus is independently associated with 90-days readmission and other clinical outcomes among patients hospitalized with heart failure.
We conducted a retrospective cohort study using the 2016-2017 Nationwide Readmissions Database to evaluate the association of systemic lupus erythematosus with 90-days readmission after heart failure hospitalization.
SLE raised 90-day readmission risk after heart failure hospitalization
Among 1,625,731 patients hospitalized with heart failure, 9096 had comorbid systemic lupus erythematosus.
Compared with non-systemic lupus erythematosus patients, those with systemic lupus erythematosus were younger (mean age 61 vs 72 years), predominantly female, and more likely to have socioeconomic disadvantage and a higher comorbidity burden.
In-hospital mortality did not differ significantly between groups; however, mortality during readmissions was nearly doubled compared with index admissions (5.4% vs 2.9%).
SLE patients had a median length of stay of 4 days (vs 4 days in non-SLE) and incurred median hospitalization costs of USD 32,872 (13% higher than non-SLE patients).
Systemic lupus erythematosus is independently associated with an increased risk of 90-days readmission following heart failure hospitalization, contributing to greater healthcare utilization and costs.
These findings highlight the need for tailored strategies for transitional care, multidisciplinary follow-up, and socioeconomic support.