Infective endocarditis following transcatheter valvular interventions (transcatheter aortic valve implantation and transcatheter edge-to-edge repair).

Clinical presentation is frequently atypical, particularly in elderly and in patients with multimorbidity, resulting in delayed diagnosis.

Echocardiography remains the first-line imaging modality but is often limited by prosthesis-related artifacts.

Multimodality imaging, particularly electrocardiography-gated cardiac computed tomography and in selected cases positron emission tomography, substantially improves diagnostic accuracy and detection, especially of perivalvular complications.