Epidemiology of Peripheral Artery Disease, Risk Factors, and Trends.

Peripheral artery disease is more common in the elderly population; prevalence increases significantly from about 10% in individuals aged 55 to 59 years to 60% among people aged ≥ 85 years.

Conventional modifiable risk factors, including smoking, diabetes mellitus, hypertension, and dyslipidemia, account for roughly 75% of peripheral artery disease cases, with the most common association being tobacco use and diabetes.

The peripheral artery disease prevalence has almost doubled between 1990 and 2021 globally.