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Cohort studyInternational journal of cardiology · 2026

Predictive value of D-dimer and multiple dual-energy CT indicators for assessing the risk of pulmonary embolism.

Huiling Hu, Peng Xie, Wei Han … Kuanyu Che

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Internal MedicineCohort study

CT pulmonary embolism index strongly predicts severe pulmonary embolism

Predictive value of D-dimer and multiple dual-energy CT indicators for assessing the risk of pulmonary embolism.

Huiling Hu … Kuanyu Che

International journal of cardiology · 2026

Purpose

Logistic regression was performed to estimate the association between D-dimer level 、the main pulmonary artery-to-ascending aorta diameter ratio, the right-to-left ventricular (RV/LV) diameter ratio, the pulmonary embolism (pulmonary embolism) index, and the perfusion defect index and pulmonary embolism risk stratification.

Methods

A retrospective analysis was conducted on the clinical data of 52 patients diagnosed with pulmonary embolism by dual-source CT pulmonary angiography in the author's hospital.

n = 52 patients

Results

AUC scale: 1.0 is perfect prediction; 0.850 indicates strong discrimination of severe cases

AUC 0.85 (95% CI 0.72 to 0.93)

null 0

0.72

0.93

CI excludes the null - significant

More results

Levels of RV/LV diameter ratio, pulmonary embolism index, and perfusion defect index were significantly higher in the severe group than in the non-severe group (P < 0.05).

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Conclusion · 1 of 3

D-dimer levels were not correlated with the risk stratification of pulmonary embolism. The RV/LV diameter ratio can serve as reference indicators for identifying severe pulmonary embolism patients.

Conclusion · 2 of 3

Both the perfusion defect index and the pulmonary embolism index demonstrated good predictive value for severe cases.

Conclusion · 3 of 3

These findings offer valuable insights for optimizing the clinical management and treatment strategies for pulmonary embolism patients.

Post

Predictive value of D-dimer and multiple dual-energy CT indicators for assessing the risk of pulmonary embolism.

CT pulmonary embolism index strongly predicts severe pulmonary embolism

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