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Cohort studyPeerJ · 2026

Predictive model for preoperative deep vein thrombosis in distal femur fractures using inflammatory blood markers: a single-center retrospective cohort study.

Xin Deng, Junfeng Wan, Xin Huang … Yang Liu

Internal MedicineCohort study

Inflammatory blood marker model predicts preoperative deep vein thrombosis in distal femur fractures

Predictive model for preoperative deep vein thrombosis in distal femur fractures using inflammatory blood markers: a single-center retrospective cohort study.

Xin Deng … Yang Liu

PeerJ · 2026

Background

The incidence of distal femur fractures (distal femur fractures) has shown a continuous annual increase.

Purpose

This study aimed to construct a predictive model utilizing inflammatory blood indicators to estimate the preoperative risk of deep vein thrombosis in patients with distal femur fractures.

Methods

A retrospective analysis was performed on 493 eligible patients treated for distal femur fractures, admitted to a single-center, between January 2022 and September 2025.

n = 205 cases

Results

distinguishes deep vein thrombosis from no-deep vein thrombosis cases with near-perfect accuracy, 1.0 is perfect

Training cohort

0.926AUC

Validation cohort

0.939AUC

More results

Incorporating age with these indicators, a predictive model was developed.

“

Conclusion · 1 of 2

Among the preoperative inflammatory indicators evaluated, NLR, lymphocyte-to-monocyte ratio, white blood cell count, neutrophil count, lymphocyte count, and eosinophil count were identified as independent determinants of preoperative lower limb deep vein thrombosis in patients with distal femur fractures.

Conclusion · 2 of 2

The predictive model constructed based on independent risk factors has excellent predictive efficacy and clinical application value.

Post

Predictive model for preoperative deep vein thrombosis in distal femur fractures using inflammatory blood markers: a single-center retrospective cohort study.

Inflammatory blood marker model predicts preoperative deep vein thrombosis in distal femur fractures

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