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New research · Cardiology
European heart journal. Digital health · 4d
Cohort studyEuropean heart journal. Digital health · 2026

Cardiology hospital admission risk prediction: training, internal validation and technical implementation in the electronic health record.

Jasper L Selder, Olivier V Witteman, Oscar M van der Meer … Cornelis P Allaart
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CardiologyCohort study

The Cardiology Hospital Admission Risk Prediction model showed strong discrimination for predicting cardiac events.

Cardiology hospital admission risk prediction: training, internal validation and technical implementation in the electronic health record.

Jasper L Selder … Cornelis P Allaart
European heart journal. Digital health · 2026
Background

Rising healthcare demand is increasingly outpacing available outpatient capacity in cardiology, where follow-up is often scheduled at fixed intervals despite substantial variation in individual patient risk.

Purpose

Rising healthcare demand is increasingly outpacing available outpatient capacity in cardiology, where follow-up is often scheduled at fixed intervals despite substantial variation in individual patient risk.

Methods

We developed and validated a machine-learning model as part of the Cardiology Hospital Admission Risk Prediction (Cardiology Hospital Admission Risk Prediction) program.

n = 52 989 unique patients
0.77
Results
0.77
The model's AUROC of 0.77 indicates strong ability to distinguish patients at risk.
n = 52 989 unique patients
More results

Accurate risk estimation using routinely collected electronic health record (electronic health record) data may support more individualized follow-up planning by identifying patients at very low risk of mortality or unplanned hospitalization, in whom follow-up intervals could be safely extended.

More results

The retrospective baseline cohort comprised 307 792 outpatient visits from 52 989 unique patients at Amsterdam UMC.

The primary endpoint was a composite of unplanned cardiac hospitalization or all-cause death within 2 years; the 1-year composite endpoint served as a secondary outcome.

“
Conclusion · 1 of 2

This study shows that machine-learning applied to routine electronic health record data can deliver clinically meaningful, visit-level risk stratification for cardiology outpatients.

Conclusion · 2 of 2

The successful electronic health record integration of Cardiology Hospital Admission Risk Prediction enables prospective evaluation of data-driven follow-up strategies aimed at reducing outpatient clinic burden through safe de-intensification of follow-up for low-risk patients.

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