Clinical Outcome of Epilepsy Surgery of The Temporal Lobe in Paediatric Group: A Retrospective Cohort Study.

Cohort studyThe Malaysian journal of medical sciences : MJMS· Dec 2025

Clinical Outcome of Epilepsy Surgery of The Temporal Lobe in Paediatric Group: A Retrospective Cohort Study.

Mohd Khairun Mohd Mispan, Azmi Alias, Ahmad Rithauddin Mohamed … Jafri Malin Abdullah

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Pulmonology & Critical CareCohort studyTreatmentQ3IF 1.7

Most children were seizure-free immediately after temporal lobe epilepsy surgery.

Clinical Outcome of Epilepsy Surgery of The Temporal Lobe in Paediatric Group: A Retrospective Cohort Study.

Mohd Khairun Mohd Mispan … Jafri Malin Abdullah

The Malaysian journal of medical sciences · Dec 2025 · Q3 in General Medicine

Background

This study was to identify seizure outcome following epilepsy surgery in paediatric group using Engel classification.

Methods

This study was a retrospective cohort study over a period of eight years from 1 January 2012 until 1 July 2019.

n = 29 patients

Results

96.6%

children were seizure-free immediately after brain surgery for seizures

n = 29 patients

More results

The mean time between seizure onset and surgery was 5.6 years.

Hippocampal Sclerosis was present in 13 patients (44.8%).

There are significant changes in post operative Anti Epileptic Medications (AEDs) reduction in this study ( P = 0.006).

More results

Possible risk factor of seizure was suggestive for less recurrence of seizure, which may become a predictor to achieve Engel I classification in this study ( P = 0.052).

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Conclusion

The surgery outcome of epilepsy surgery of the temporal lobe in paediatric group was comparable in this study. Careful patient selection by multidisciplinary evaluations is mandatory.

Clinical Outcome of Epilepsy Surgery of The Temporal Lobe in Paediatric Group: A Retrospective Cohort Study.

Clinical Outcome of Epilepsy Surgery of The Temporal Lobe in Paediatric Group: A Retrospective Cohort Study.

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