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New research · Otolaryngology (ENT)
Psycho-oncology · 1d
ObservationalPsycho-oncology · 2026

Otolaryngologic Symptom Burden, Emotional Distress, and Stigma in Nasopharyngeal Carcinoma Survivors: A Prospective Cohort Study.

Yi-Lun Shih, Chung-Ying Lin, Wei-Chih Chen … Ching-Nung Wu
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Otolaryngology (ENT)Observational

Emotional well-being is associated with self-stigma in nasopharyngeal carcinoma survivors.

Otolaryngologic Symptom Burden, Emotional Distress, and Stigma in Nasopharyngeal Carcinoma Survivors: A Prospective Cohort Study.

Yi-Lun Shih et al. · Psycho-oncology · 2026
Purpose

To examine whether otolaryngology-specific symptom burden is associated with perceived and self-stigma among nasopharyngeal carcinoma (NPC) survivors, and the mediating role of emotional well-being.

Methods

Kaohsiung Chang Gung Memorial Hospital, Taiwan.

n = 340 NPC survivors
Results
worse emotional well-being was associated with higher self-stigma
n = 340 NPC survivors
More results

PS > 0 occurred in 8.0% of assessments, whereas high SS (> 2.5) was present in 9.5%.

High-stigma groups exhibited significantly worse symptom trajectories.

Mediation analyses indicated full mediation of most symptom-PS associations and partial mediation of symptom-SS associations by the emotional domain.

“
Conclusion

Emotional well-being may be an important correlate of both perceived and self-stigma in NPC survivorship. Whether addressing emotional well-being can reduce stigma warrants evaluation in future studies.

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